BMBDG Seminar: Ph.D. Exit Seminar – Jibin Sadasivan and Reid Warsaba
Jibin Sadasivan Title: When proteins go viral: Investigation on how a viral protein impairs stress granule formation Abstract: Stress granules (SG) are ribonucleoprotein aggregates that accumulate during cellular stress when translation is limited. Inhibition of SG assembly has been observed under virus infection across species, suggesting a conserved fundamental viral strategy. How this occurs and why […]
BMBDG Seminar: Dr. Tom Hobman
Title: Unraveling RNA virus-host interactions reveals novel antiviral targets. Professor. Department of Cell Biology. University of Alberta Abstract: RNA virus infections impose huge economic and social burdens around the globe. Direct-acting antiviral therapeutics and vaccines can be highly effective in controlling epidemic and pandemic viruses, but these drugs/prophylactics take time to develop and their efficacy is […]
BMBDG Seminar: P.h.D Exit Seminar – Amy Strilchuk (Cancelled)
Title: Blood clot stability can be controlled using lipid nanoparticle-delivered siRNA Abstract: Disruptions in the balance of clot formation and degradation can lead to dangerous, potentially fatal, clotting or bleeding events. While a plethora of research tools and clinical therapies exist to control clot formation, options for controlling clot degradation are extremely limited. RNA and lipid-based technologies […]
BMBDG Seminar: Dr. Roberto Chica
Title: Ensemble-based computational design of enzyme catalysis and conformational equilibrium. Professor, Department of Chemistry and Biomolecular Sciences. University of Ottawa Abstract: Enzymes are dynamic molecules, and this flexibility is essential to their catalytic function. Yet, computational enzyme design is typically performed using a single protein scaffold as design template, ignoring the important contributions of dynamics […]