I obtained my Ph.D. in Biochemistry from University of Victoria in Dr. Stephen Evans’ Laboratory. My research focused on the structural determination of several antibody fragments in complex with their antigens, to gain insights into both the genesis of autoimmune diseases via infection with Gram-negative bacteria, as well as Chlamydial lipopolysaccharide recognition.
I am now working on an ion channel protein (Ryanodine Receptor) which is involved in the beating of our hearts, as a post-doctoral project in the Dr. Filip Van Petegem’s laboratory at the University of British Columbia. We employ X-ray crystallography with ancillary methods including electrophysiology, isothermal calorimetry, and electron microscopy in order to study the mechanism responsible for the opening and closing of this channel protein. This ion channel is among the largest genes known with literally hundreds of mutations documented to cause arrhythmias. In collaboration with several cardiologists who specialize in arrhythmias, our lab aim to determine how the various mutations in this gene (and other proteins) lead to the arrhythmias as a step to developing therapeutics.
Jordan Shimell Jordan completed his B.Sc. in Molecular Biology and B.A. in Psychology at Simon Fraser University. He is currently a graduate student in the Bamji Lab with an interest in the molecular underpinnings of neurological diseases. Specifically, he utilizes cellular and molecular techniques in conjunction with microscopy to investigate the formation, elimination, and remodelling of synapses in primary hippocampal cultures. His research is currently focused on understanding neurite outgrowth and synapse formation in X-linked mental retardation.
Roy van der Meel Roy obtained his PhD from Utrecht University in The Netherlands. He is currently a postdoc in the Cullis lab where he focuses on the development of a nanomedicine combination treatment for prostate cancer.
John Young John is a PhD student in Dr. Franck Duong’s lab. His research focus is on mechanisms of Sec-dependent protein transport in E. coli.