“Epigenetic Control in Chromosome Segregation: @ Centromere and Sister Chromatid Cohesion”, by Karen Wing Yee Yuen, Assistant Professor, School of Biological Sciences , University of Hong Kong. Each chromosome must segregate equally to the two daughter cells in every cell cycle. Errors in chromosome segregation can lead to aneuploidy in cancers and chromosome abnormality disorders. […]
“Characterizing the assembly and molecular interactions of the fission yeast Atg1 autophagy regulatory complex”, by Tamiza Nanji, PhD Candidate, Yip Lab. Abstract: Macroautophagy, often referred to as autophagy, is a non-selective degradation mechanism used by eukaryotic cells to recycle cytoplasmic material and maintain homeostasis. Upregulated under starvation to generate molecular building blocks for ongoing cellular […]
“Characterizing the assembly and molecular interactions of the fission yeast Atg1 autophagy regulatory complex,” by Tamiza Nanji, Candidate Yip Lab. Abstract: Macroautophagy, often referred to as autophagy, is a non-selective degradation mechanism used by eukaryotic cells to recycle cytoplasmic material and maintain homeostasis. Upregulated under starvation to generate molecular building blocks for ongoing cellular processes, […]
“Characterizing a Peculiar Mutant of T4 Lysozyme”, by Jacob Brockerman, PhD Candidate, McIntosh Lab. T4 phage lysozyme (T4L) is an enzyme that cleaves bacterial cell wall peptidoglycan. Remarkably, the single substitution of the active site Thr26 to a His (T26H) converts T4L from an inverting to a retaining glycoside hydrolase with transglycosylase activity. It has […]
“Adipocyte Control of Energy Balance” by Lawrence Kazak, Assistant Professor, Department of Biochemistry, McGill University, Rosalind and Morris Goodman Cancer Research Centre The obesity pandemic has precipitated a steep rise in metabolic diseases such as type 2 diabetes, heart disease, and many cancers. Globally, 40% of adults are overweight and 15% are obese. Obesity occurs […]
“Moonlighting tRNA synthetases as extracellular targets of matrix metalloproteinases, ” by Parker Jobin, MD/PhD Candidate, Overall Lab. Wednesday, May 22, 2019 at 9:00 am in Room 200 of the Graduate Student Centre, 6371 Crescent Road.
“Characterization of Interaction between Ty1 Integrase and RNA Polymerase III For Ty1 Retrotransposon Insertion Into the Yeast Genome“, by Stephanie Cheung, PhD candidate in the Measday Lab. Thursday, August 15, 2019 at 12:30 in Room 203, Graduate Student Centre, 6371 Crescent Road. Abstract Retrotransposons are eukaryotic mobile genetic elements that transpose by reverse transcription of […]
“Small Molecules Effective for Disruption of HIV-1 Latency“, by Seyedeh Pargol Hashemi, PhD candidate in Sadowski Lab. Tuesday, August 20, 2019 at 9:00 am, Room 203, Graduate Student Centre, 6371 Crescent Road. Abstract Although antiretroviral therapies have improved the outlook of the HIV epidemic by controlling virus replication, they do not provide a cure. […]
“Charting metabolism in health and disease by activity metabolomics and nanostructure imaging mass spectrometry,” by Amelia Palermo, post-doctoral scientist. Department of Biochemistry and Molecular Biology and BC Children’s Hospital presents Amelia Palermo, candidate for joint Faculty position in BMB and BCCHRI. Amelia is currently a post-doctoral scientist at The Scripps Research Institute Center for Metabolomics […]
“Differential transporter utilization facilitates nutrient crosstalk and creates a targetable metabolic niche in cancer,” by Seth Parke, Post-Doctoral Fellow, New York University School of Medicine, Alec Kimmelman Lab. Department of Biochemistry and Molecular Biology and BC Children’s Hospital presents Seth Parker, candidate for joint Faculty position in BMB and BCCHRI. Seth Parker received his B.S. […]