Title: Unraveling RNA virus-host interactions reveals novel antiviral targets.
Professor. Department of Cell Biology.
University of Alberta
Abstract: RNA virus infections impose huge economic and social burdens around the globe. Direct-acting antiviral therapeutics and vaccines can be highly effective in controlling epidemic and pandemic viruses, but these drugs/prophylactics take time to develop and their efficacy is often limited to specific viral strains. To minimize the impact of future emerging RNA viruses, a stockpile of broad-spectrum antivirals is required to serve as a first line of defense against these pathogens. Identification of host cell-based pathways that are exploited or inhibited by multiple viruses is expected to reveal novel targets for antiviral therapy. Using targeted and unbiased screening approaches, we have identified multiple host cell pathways that can be pharmacologically inhibited or enhanced to reduce infection by multiple RNA viruses including SARS-CoV-2..
Monday, September 26, 2022 at 2:30 pm at LSC 3 and Zoom
Hosted by: Dr. Eric Jan