BMBDG Seminar: PhD Exit Seminar – David Rattray

Title: Proteomic Method Development for Studying Salmonella-Host Protein Interactions.

Salmonella is a pathogen of humans and animals. Pathogenesis is mediated by effector proteins that are translocated into host cells. These effector proteins interact with host proteins and cellular processes to establish a replication permissive niche for the bacterium. Efforts to determine the roles of the effector proteins have revealed many insights, however the understanding of the interaction between host and pathogen is incomplete. To further investigate the impact of Salmonella effector proteins on host cells, we developed high throughput proteomic methods to assess changes that occur during infection. 

Monday, March 28, 2022 at 2:30 pm via Zoom.

Hosted by: Dr. Leonard Foster