Professor, Biochemistry and Molecular Biology, The University of British Columbia
Professor, Chemistry, The University of British Columbia
Email: stephenson@chem.ubc.ca
Website: https://www.thestephensongroup.org/
X: https://x.com/crjsteph
Research Interest
Our group is interested in developing methodologies that harness the power of visible light to mediate reactions that are useful for the synthesis of biologically active molecules. We conduct photo- and electrochemical reactions in both batch and continuous flow manifolds with the goal of developing methods to access unique chemical space.
The Stephenson lab is dedicated to maintaining a climate of inclusivity, mutual respect, and understanding. We believe that diversity is the cornerstone of innovation as it allows people from distinct backgrounds to contribute their experiences to the chemical problem-solving process, whether it be an idea for a useful synthetic method or a novel way of disconnecting a natural product.
Publications
Comprehensive List
Selected Publications
“A general alkene aminoarylation enabled by N-centered radical reactivity of sulfinamides.” Noten, E. A.; Ng, C. H.; Wolesensky, R. M.; Stephenson, C. R. J. Nat. Chem. 2024, 16, 599.
“Revisiting the Reactivity of the Dismissed Hydrogen Atom Transfer Catalyst Succinimide-N-oxyl.” Yang, C.; Farmer, L.; Pratt, D. A.; Maldonado, S.; Stephenson, C. R. J. J. Am. Chem. Soc.2024, 146, 12511.
“High-Throughput Optimization of Photochemical Reactions using Segmented Flow Nanoelectrospray Ionization Mass Spectrometry.” Sun, A. C.; Steyer, D. J.; Robinson, R. I.; Ginsburg-Moraff, C.; Plummer, S.; Gao, J.; Tucker, J. W.; Alpers, D.; Kennedy, R. T.; Stephenson, C. R. J. Angew. Chem. Int. Ed. 2023, e202301664
“Arylsulfonylacetimides as Bifunctional Reagents for Alkene Aminoarylation.” Monos, T. M.; McAtee, R. C.; Stephenson, C. R. J. Science 2018, 361, 1369.
“Synthesis of Resveratrol Tetramers via a Stereoconverent Radical Equilibrium.”Keylor, M. H.; Matsuura, B. S.; Griesser, M.; Chauvin, J.-P.; Harding, R. A.; Kirillova, M. S.; Zhu, X.; Fischer, O. J.; Pratt, D. A.; Stephenson, C. R. J. Science2016, 354, 1260.