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Why PhD and MSc program in BIMB, UBC?
We offer a stimulating environment to prepare you for a scientific research career. For incoming September 2015 candidates, we have two $7,500 Entrance Scholarship Awards to be awarded to the top 2 applicants.
Season’s Greetings
Season’s Greetings, Joyeuses Fêtes, Saludos de la estación, Auguri di Buone Feste, Weihnachtsgrüße, 季節的問候, Säsong hälsningar, Groeten van het Seizoen, ….
Biochemistry and Molecular Biology office will be closed for the holidays, from noon Wednesday, December 24 and will re-open Monday, January 5, 2015.
Special Seminar – Rome Voulhoux
“Towards a better understanding of the bacterial type II secretion pathway”, Romé Voulhoux, LISM UMR7255, CNRS Marseille, France. Thursday, December 4, 2014 @ 3:00 pm, LSC #3, 2350 Health Sciences Mall
Hosted by Dr. Franck Duong
Abstract
The bacterial type II secretion system (T2SS) is unique in its ability to promote the transport of large folded and sometimes multimeric proteins. In this secretion process, exoproteins are first translocated into the periplasm. The final release into the medium requires a multiprotein complex called the secreton. Although the 12 individual components of the secreton have been identified, its mode of action remains obscure. We set up various dedicated in vitro and in vivo protein-protein interaction experiments to identify the Pseudomonas aeruginosa Xcp T2SS periplasmic interactome. BIAcore experiments revealed that three Xcp components, XcpP, the secretin XcpQ, and the pseudopilus tip, directly and specifically interact with secreted exoproteins. Affinity chromatography co-purification indicated that XcpY and XcpZ periplasmic domains also interact with the secreted substrate. Altogether, our results allowed us to propose the most advanced integrative model of Xcp T2SS assembly and function.
BMB and CPS DG Seminar – Anne-Claude Gingras
“Signaling interactome dynamics in health and disease,” by Anne-Claude Gingras, Senior Investigator, Lunenfeld-Tanenbaum Research Institute. Molecular Genetics, University of Toronto. Thursday, December 4, 2014 @ 12:30 pm, LSC #3, 2350 Health Sciences Mall.
BMBDG Seminar – Nancy Forde
“Force as a tool to probe protein structure and interactions”, by Nancy Forde, Associate Professor, Department of Physics, Simon Fraser University. Monday, November 17, 2014 @ 3:00 pm, LSC #3, 2350 Health Sciences Mall.
BMBDG Seminar – Justin Kollman
“Structure of CTP Synthase Filaments: a novel mechanism of enzyme regulation”, by Justin Kollman, Assistant Professor, Department of Biochemistry, University of Washington. Monday, November 24, 2014 @ 3:00 pm, LSC #3, 2350 Health Sciences Mall
BMBDG Seminar – Joerg Gsponer
“Bringing order to protein disorder”, by Joerg Gsponer, Assistant Professor, Department of Biochemistry and Molecular Biology, UBC. Monday, November 10, 2014 @ 3:00 pm, LSC #3, 2350 Health Sciences Mall
10th Annual Michael Smith Distinguished Research Lecture: Dr. Robert T Sauer
“Machines of Protein Destruction” by Robert T Sauer, Luria Professor of Biology, MIT. Monday, December 8 at 4:00 pm LSC, #1, 2350 Health Sciences Mall.