“Structural insights into the dynamic process of G protein coupled receptor activation”, by Dr. Brian Kobilka, MD, Stanford University. Nobel prize in Chemistry, 2012.
Monday, September 18, 2017 at 4:00 pm, LSC #1, 2350 Health Sciences Mall.
Co-sponsored by Michael Smith Laboratories and Biochemistry and Molecular Biology.
Republished from Faculty of Medicine News
Leonard Foster, Professor and Interim Head of the Department of Biochemistry and Molecular Biology, has been named the recipient of the 2017 Genome BC Award for Scientific Excellence.
This award honours an individual, group or company in B.C. whose work has had a significant impact on advancing the fields of genomics, proteomics, bioinformatics or systems biology.
Dr. Foster’s research is focused on quantitative proteomics using LC-ESI-MS to study biological systems. His research covers a wide range of topics including pathogen invasion, infection, protein localization and mapping protein interaction. He is currently working on a number of projects including finding host targets of effector proteins secreted from pathogenic bacteria and identifying biomarkers of disease resistance in honey bees.
To learn more about Dr. Foster’s research read: Breeding a Sweet Solution
A formal presentation of this award will take place during the Annual Life Sciences BC Awards ceremony on Wednesday, April 19, 2017.
“Identification of Novel Picornavirus Proteinase Substrates Using Terminal Amine Isotopic Labeling of Substrates”, by Dr. Julienne Jagdeo, Jan Lab.
Monday, June 19th, 2017 at 3:00 pm, LSC#3, 2350 Health Sciences Mall.
“Understanding ETS transcription factors: from ordered domains to disordered sequences,” by Dr. Desmond Lau, McIntosh Lab.
Monday, June 12th, 2017, 3:00 pm, LSC #3, 2350 Health Sciences Mall
“Lateral lipid organization in Model membranes,” by Peter Tieleman, Professor, Biochemistry, University of Calgary.
Wednesday, June 7th, 2017 at 3:00 pm. LSC #3, 2350 Health Sciences Mall.
“Expanding the biological roles of the Saccharomyces cerevisiae KAT NuA4 through systems biology,” by Kristin Baetz, Professor, Department of Biochemistry, Microbiology and Immunology and Director of Ottawa Institute of Systems Biology, University of Ottawa.
Monday, June 5th, 2017 at 3:00 pm, LSC #3, 2350 Health Sciences Mall.
“Understanding ETS transcription factors: from ordered domains to disordered sequences,” by Desmond Lau, PhD Candidate, McIntosh Lab.
Wednesday, May 31, 2017 at 12:30 pm Room 207, Anthropology and Sociology Building, 6303 North West Marine Drive.
“Host and Viral Determinants of Viral RNA Accumulation: from Hepatitis C Virus to Zika Virus”, Selena Sagan, Assistant Professor, McGill University.
Hepatitis C virus (HCV) and Zika virus (ZIKV) represent a significant threat to global health. As positive-sense RNA viruses, their viral genome itself must serve as a template for viral translation, replication, and packaging. However, how these viruses coordinate and regulate uses state-of-the-art approaches to study RNA-RNA and protein-RNA interactions important to the life cycle of these viruses. We aim to understand: Which regions of the genome mediate these events? How are these events regulated? What host/viral factors are involved? How can we interrogate these protein-RNA and RNA-RNA interactions on a genome-wide scale? How can we interfere with these processes? What can this teach us about cellular RNA regulation? This research will further our understanding of viral RNA accumulation, host-virus interactions, novel mechanisms of RNA regulation, and may provide new avenues for antiviral intervention for these important human pathogens
Hosted by Dr. Eric Jan
Thursday, May 25, 2017 at 10:00 am, LSC#3, 2350 Health Sciences Mall.
“Control of gene expression by novel RNA modifications and cytoplasmic sequestration,” by Robert Walters, PhD, Postdoctoral Fellow, University of Colorado.
Hosted by Dr. Leonard Foster
Thursday, May 11, 2017 at 10:00 am, LSC #3, 2350 Health Sciences Mall, UBC
“Transcriptional memory through the cell cycle.” by Sheila Teves, Postdoctoral Fellow, University of California, Berkley.
Epigenetic maintenance of cell-type specific transcription programs is a key component of cell identity. However, this maintenance is challenged during mitosis in at least three ways. First, the transcription machinery is inactivated, leading to global transcription inhibition. Second, chromatin compacts into highly condensed mitotic chromosomes resulting in decreased DNA accessibility. Third, transcription factors (TFs) are believed to be excluded from mitotic chromosomes. Following mitosis, how do daughter cells faithfully re-establish the cell-type specific transcription program? Recent discoveries that a select set of TFs remain bound on mitotic chromosomes suggest a potential mechanism for maintaining transcriptional programs through the cell cycle termed mitotic bookmarking. I will discuss the roles of sequence-specific TFs and the general Pol II machinery in facilitating transcriptional memory in mouse embryonic stem cells.
Hosted by Dr. Leonard Foster
Monday, May 8, 2017 at 10:00 am, LSC#3, 2350 Health Sciences Mall, UBC.